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Showing posts from May, 2014

A review of The Future of the Mind: The Scientific Quest to Understand Enhance, and Empower the Mind

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The Future of the Mind , authored by physicist Dr. Michio Kaku , explores how neuroscience might inform questions that philosophers have been debating for centuries: Do we have a soul? What happens after we die? Do we even have to die? And what would it take to produce a robot with human consciousness or emotions? To explore these questions, Dr. Kaku interviewed hundreds of scientists who are actively conducting ground breaking work in labs around the world, and from these conversations he made predictions on how these scientific findings would shape our future. The work that Dr. Kaku discusses, such as the latest advances in brain-computer-interfaces (BCI) for the disabled , 1 recording dream images with MRI machines , 2 or implanting memories in mice , 3,4 makes for a fascinating and engrossing read from start to finish. The Future of the Mind is at its best when taking readers through these areas of research and explaining the long-term significance, however many of the neurophi...

Translating Preclinical Test Results into “Real World” Consequences

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By Jalayne J. Arias, JD, MA Jalayne J. Arias is the Associate Director of the NeuroEthics Program and Assistant Professional Staff in the Department of Bioethics at the Cleveland Clinic. Ms. Arias’ work incorporates empirical and conceptual projects addressing critical legal and ethical issues inherent in diagnosing, treating, and researching Alzheimer’s disease and other neurodegenerative conditions. Most recently, she served as the principal investigator for the study Stakeholders’ Perspectives on Preclinical Alzheimer’s Diagnosis: Patients, Families and Care Givers . Her recent publication, Confidentiality in preclinical Alzheimer disease studies (Neurology), addresses confidentiality concerns relevant to biomarker testing in Alzheimer’s. In 2007, Dr. Dubois and co-authors introduced the concept of prodromal Alzheimer’s disease in their Lancet article revising diagnostic criteria. In 2011, the National Institutes of Aging and the Alzheimer’s Association supported a series of...

When is diminishment a form of enhancement? Another twist to the “enhancement” debate in biomedical ethics

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By Brian Earp, MSc Photo by Rob Judges Brian Earp is a Research Fellow at the Uehiro Centre for Practical Ethics at the University of Oxford. He is an interdisciplinary researcher with training in cognitive science, experimental (social) psychology, philosophy, and ethics. With Professor Julian Savulescu , Brian is writing a book on the neuroenhancement of love and marriage, to be completed this year. There is a big debate going on about “enhancement.” For many years now, people have realized that new technologies, along with discoveries in neuroscience and pharmacology, could be used in ways that seem to go beyond mere “medicine” – the treating of deformity or disease. Instead, to use a phrase popularized by Carl Elliot, they could make us “better than well.” Faster, stronger, smarter, happier. Quicker to learn, slower to forget. It has even been suggested that we could use these new technologies to “enhance” our love and relationships , or make ourselves more moral .  These ki...

(en)Gendering psychiatric disease: what does sex/gender have to do with posttraumatic stress disorder (PTSD)?

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Mallory Bowers is a 5th year Neuroscience doctoral candidate working with Dr. Kerry Ressler at Emory University. Prior to graduate school, Mallory received her Bachelor of Arts from the University of Pennsylvania. Mallory is interested in behavioral neuroscience, with a particular focus on how neural plasticity contributes to learning. With Dr. Ressler, Mallory is using a mouse model of exposure-based psychotherapy to better understand the neurobiology of learned fear. Specifically, her research focuses on a potential interaction between the cholecystokinin and endogenous cannabinoid systems that may underlie extinction of cued fear. Mallory was on the organizing committee for the 2013 “Bias in the Academy” Conference and is President of Emory Women in Neuroscience (E-WIN). As I’ve become more entrenched in the PTSD field, I’ve been struck by the prominent sex/gender difference in the prevalence of PTSD (among many other psychiatric disorders) and the categorical use of male animal m...