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Showing posts with the label epigenetics

Is trauma in our genes? Ethical implications of epigenetic findings

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by Neil Levy Neil Levy is professor of philosophy at Macquarie University, Sydney and deputy director of the Oxford Centre for Neuroethics . He is the author of 7 books, including Neuroethics (2007) and Consciousness and Moral Responsibility (2014), and edits the journal Neuroethics . He is also a member of the AJOB Neuroscience board. A recent study by Rachel Yehuda et al. in Biological Psychiatry provided further evidence for the genetic transmission of acquired characteristics, by showing that Holocaust survivors passed certain acquired genetic markers to their children. The idea that acquired characteristics can be genetically transmitted is (roughly) equivalent to the doctrine of Lamarckism , and was long considered a heresy in biology. [Editor's note: see also Ryan Purcell's 2014  post for this blog on the relationship between Lamarckism and epigenetics .] According to the Darwinian orthodoxy, traits change because randomly occurring mutations confer a relative fitnes...

Early Intervention in Schools: A Site for Empirical Neuroethics

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By Ilina Singh, MSc Ilina Singh is a Professor of Science, Ethics, and Society in the department of Social Science, Health, and Medicine at King’s College London, and is cross-appointed to the Institute of Psychiatry . Her work examines the psycho-social and ethical implications of advances in biomedicine and neuroscience for young people and families. She is also a member of the AJOB Neuroscience Editorial Board.   The developmental logic of early intervention is currently all the rage across child care-related sectors, including education, mental health, juvenile justice and social policy. It’s not a new logic by any means (witness longstanding programmes such as HeadStart ), but it has new energy and justification with the emergence of epigenetic theories of development. Epigenetics has brought attention to ‘environment’ to the fore, particularly in pediatrics and in child psychiatry. While epigenetic theories are still that – theories – the last few years have seen a surge...

Do prison sentences alter oxytocin levels?

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Editor’s Note: Guest post by NEWest Leader, Livia Merrill Livia Merrill is a recent graduate from Tulane University in New Orleans, LA, where she has received both her B.S. and M.S. in Neuroscience. Her research of 4 years under Dr. Fiona Inglis, PhD , consisted of dendritic morphological changes in the prefrontal cortex of non-human primates after the administration of PCP. Having psychomimetic effects, this model was utilized to contribute to the study of schizophrenia and to provide for more effective anti-psychotics. Her current pursuit is under Dr. Stacy Drury, PhD to examine cortisol levels of pregnant mothers in some of the underprivileged neighborhoods of New Orleans and the epigenetic effects on their offspring. Livia’s future plans consist of research behind deviant behavior and rehabilitating subjects. Ideally, she hopes to contribute to change in the criminal justice system, where punishment can transition to rehabilitation, by demonstrating the negative effects of adver...

Lamarckian sh*t? Why epigenetics is not eugenics

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An argument could be made that communicating scientific advances to the public has never been more important. As the NIH budget stagnated, and then was cut by Sequestration, many of us have realized what a poor job we have been doing convincing the public of the importance of basic science research. Neuroscience itself has been under more scrutiny recently. As Adam Gopnik of The New Yorker wrote in a review of three new books bashing brain research, “Neuroscience can often answer the obvious questions but rarely the interesting ones.” If that is the way that the public sees it, then clearly we are losing something in translation. Recently there has been a push to reverse this trend and reaffirm biomedical research as a source of inspiration and hope for the public. The actor and author Alan Alda, who has long held a passion for science, has made it a personal mission to improve communication about science because “How are scientists going to get money from policy makers, if ...

Refried serotonin lunch

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That title sounds like the prequel to a William Burroughs novel. I wish I'd come up with it myself, but I'm actually plagiarizing almost word for word from Dr. Steven Hyman, Director of the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard. Last week, Emory awarded Dr. Hyman this year's Neuroscience and Ethics Award. Dr. Hyman spoke on "Addiction as a Window on Volitional Control", which shouldn't be surprising, given his molecular and genetic studies of the dopaminergic system. Earlier in the day, Dr. Hyman stopped by the Emory Center for Ethics to have lunch with faculty and students from several schools and programs. He held forth on the state of translational neuropsychiatric research for an hour and a half, while the rest of us prevented him from eating by constantly barraging him with questions. I have a feeling I'm not the only one who found what he had to say both thought-provoking and provocative. He liberally spice...