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Showing posts with the label depression

Allies and Enemies in the Fight for Mental Health Reform

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  By Nathan Ahlgrim The Need for Allies Image courtesy of Wikimedia Commons . Mental healthcare in the United States is in need of serious reform. Mental healthcare is less accessible than other services , and efforts to repeal the Affordable Care Act could put adequate care out of reach for millions more Americans. Opposition to mental healthcare reform comes from all sides, with the popular talking points demanding law and order, fiscal responsibility, and moral accountability. Still, the consequences of un- or under-treated people interacting with un- or under-trained authorities are hard to ignore, most strikingly in the criminal justice system. Americans with mental illnesses are sixteen times more likely to be shot by police , and more than half of all inmates in America suffer from mental health problems. Mental health reform, then, stands to benefit the healthcare system, criminal justice, and family structure itself. Given the opposition, legislative policy victories wil...

Revising the Ethical Framework for Deep Brain Stimulation for Treatment-Resistant Depression

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By Somnath Das Somnath Das recently graduated from Emory University where he majored in Neuroscience and Chemistry. He will be attending medical school at Thomas Jefferson University starting in the Fall of 2017. Studying Neuroethics has allowed him to combine his love for neuroscience, his interest in medicine, and his wish to help others into a multidisciplinary, rewarding practice of scholarship which to this day enriches how he views both developing neurotechnologies and the world around him.  Despite the prevalence of therapeutics for treating depression, approximately 20% of patients fail to respond to multiple treatments such as antidepressants, cognitive-behavioral therapy, and electroconvulsive therapy (Fava, 2003). Zeroing on an effective treatment of “Treatment-Resistant Depression” (TRD) has been the focus of physicians and scientists. Dr. Helen Mayberg ’s groundbreaking paper on Deep Brain Stimulation (DBS) demonstrates that electrical modulation an area of the brain ...

"Inflammation might be causing depression": Stigma of mental illness, reductionism, and (mis-)representations of science

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by Katie Givens Kime Image courtesy of Flickr “ Is depression a Kind of Allergic Reaction? ” Provocative headlines like these appear throughout popular media. Besides misrepresenting scientific findings, such journalistic coverage impacts perceptions of mental illness, as well as expectations of those seeking treatment. In last month’s Neuroethics in the News talk, Dr. Jennifer Felger , from Emory’s Department of Psychiatry and Behavioral Sciences, shared her experiences and insights on the translation (and mistranslation) of research by journalists. In relating the story of her own interactions with the media, Felger emphasized the complex and varying transactional relationships between journalists and scientists. The impact of such coverage carries notable neuroethical dimensions, potentially affecting the capacity for agency and/or aspects of a sense of self for a person experiencing mental illness. The work of Felger and others on the role of inflammation in depression emerges ...

Should Getting High be a Possible Treatment for Depression?

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By Maria Paula Martinez This post was written as part of a class assignment from students who took a neuroethics course with Dr. Rommelfanger in Paris of Summer 2016. Maria Paula Martinez is a student of a joint degree program majoring in Neuroscience and Behavioral Biology at Emory University and Biomedical Engineering at Georgia Institute of Technology. She is 20 years old and originally from Bogota, Colombia. What if instead of the traditional and usually ineffective serotonin-reuptake inhibitors ( SSRIs ) used to treat depression, we could provide patients with a drug that directly mimics the effects of serotonin, the “happiness neurotransmitter”? Not only have such compounds been around for over a millennium, but they are the active ingredients in psychedelic drugs such as magic mushrooms. A scientific paper released in The Lancet Psychiatry this past May opened the possibility for compounds like psilocybin , the active ingredient of “shrooms”, to potentially treat depression. A g...

Animal Models and the Future of Psychiatric Research

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"Few medicines, in the history of pharmaceuticals, have been greeted with as much exultation as a green-and-white pill containing 20 milligrams of fluoxetine hydrochloride — the chemical we know as Prozac" wrote Columbia University Assistant Professor of Medicine Siddhartha Mukherjee in a recent New York Times editorial on antidepressant efficacy. As Dr. Mukherjee points out, the rise of antidepressants over the past several decades has been swift and staggering. A recent CDC study found that antidepressants are the most commonly prescribed drug for Americans between 18 and 44 years of age, with 11% of Americans over the age of twelve utilizing such medications. Original image from the Global Information Exchange Network In light of such overwhelming usage rates, one would think that pharmaceutical companies would be falling over themselves to invent the next antidepressant superdrug. As it turns out, however, exactly the opposite trend is emerging. Pharmaceutical giants Ast...